Lime essential oil has a fresh, sweet citrus peel odor. Originally from Asia, lime is cultivated in many warm countries, including those in the Americas. Lime essential oil may be used as a disinfectant and detoxifying agent. It is used to treat sore throats and the flu. Its astringent, toning and refreshing properties help clear oily, congested skin. When diffused, it may help with mental fatigue, depression and apathy.